Message boards : Science : Gibbs sampler
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Robert H Send message Joined: 27 Oct 14 Posts: 38 Combined Credit: 251,816 DNA@Home: 31,083 SubsetSum@Home: 220,734 Wildlife@Home: 0 Wildlife@Home Watched: 0s Wildlife@Home Events: 0 Climate Tweets: 0 Images Observed: 0   | |
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What is Gibbs sampler? I know from past that some genes are on and som are off but i need deeper understanding of how it works. | |
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Travis Desell Volunteer moderator Project administrator Project developer Project scientist Send message Joined: 16 Jan 12 Posts: 1813 Combined Credit: 23,514,257 DNA@Home: 293,563 SubsetSum@Home: 349,212 Wildlife@Home: 22,871,482 Wildlife@Home Watched: 212,926s Wildlife@Home Events: 51 Climate Tweets: 21 Images Observed: 774       | |
What is Gibbs sampler? I know from past that some genes are on and som are off but i need deeper understanding of how it works. Hi Robert, Gibbs Sampling is a markov chain monte carlo style sampling algorithm. Basically what our gibbs sampler is doing is making probabilistic sampling walks in the DNA sequences we send out, looking for areas that the DNA sequences have in common. As DNA is kind of messy, we can't look for exact matches, and Gibbs sampling gives us a way to find semi-matched areas across all the samples. At the end of the sampling walks, the areas that were sampled the most have the highest potential to be protein binding sites. Hope that helps and let me know if you have any other questions! --Travis | |
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Message boards : Science : Gibbs sampler